Tirzepatide is a new dual receptor agonist drug, mainly used to treat type 2 diabetes and obesity
Mechanism of action:
Tirzepatide is a dual receptor agonist of GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1), which can:
Enhance insulin secretion (lower blood sugar)
Inhibit glucagon secretion (reduce liver glucose output)
Delay gastric emptying (increase satiety)
Reduce appetite and food intake (help lose weight)
Indications
Type 2 diabetes
As an adjunct to diet and exercise to improve blood sugar control.
Obese or overweight
Suitable for obese patients with BMI ≥ 30 kg/m², or overweight patients with BMI ≥ 27 kg/m² and related metabolic diseases (such as hypertension, hyperlipidemia).
Dosage and administration
Starting dose: 2.5 mg (gradually increase to reduce gastrointestinal side effects).
Maintenance dose: 5 mg, 10 mg or 15 mg, depending on blood sugar control or weight loss effect.
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