Semaglutide belongs to a class of medications known as glucagon-like peptide-1 receptor agonists, or GLP-1 RAs. It mimics the GLP-1 , released in the gut in response to eating.
Semaglutide mimics the action of GLP-1, a natural hormone involved in regulating blood sugar and appetite. By binding to GLP-1 receptors, it:
Stimulates insulin production: This helps lower blood sugar when needed.
Reduces liver sugar production: This further helps manage blood sugar levels.
Slows down digestion: This promotes a feeling of fullness and reduces appetite.
May enhance satiety and appetite control: By activating receptors in the brain responsible for appetite regulation.
One role of GLP-1 is to prompt the body to produce more insulin, which reduces blood sugar (glucose).
But GLP-1 in higher amounts also interacts with the parts of the brain that suppress your appetite and signal you to feel full. When used in conjunction with diet and exercise, it can cause significant weight loss - and a reduced risk of cancer, diabetes and heart disease- in people who are obese or overweight.
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